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A Guide to the Monoclonal Antibody Production Process

A Guide to the Monoclonal Antibody Production Process The production of monoclonal antibodies (mAbs) involves the use of cell cultures with optimized conditions for growth to generate a target molecule. Then, various additional steps follow to isolate and purify this molecule. At Cell Culture Company, we are here to support you in the monoclonal antibody … Continue reading A Guide to the Monoclonal Antibody Production Process

Optimizing Cell Culture with GMP for Advanced Research

Optimizing Cell Culture with GMP for Advanced Research In the area of cell culture research, adhering to good manufacturing practice (GMP) guidelines is essential. These guidelines, as defined by regulatory bodies like the Food and Drug Administration (FDA) and the European Medicines Agency (EMA), ensure the safety and quality of cells. At Cell Culture Company, … Continue reading Optimizing Cell Culture with GMP for Advanced Research

Effective Strategies for Cell Line Storage and Management

Effective Strategies for Cell Line Storage and Management Given the importance of cell banks to the diagnostic, research and pharmaceutical industries, it’s essential to implement best practices to safeguard your materials against introducing variability and contamination. Here are three effective strategies for cell line storage and management that reputable cell bank facilities utilize. Cell-Line Authentication … Continue reading Effective Strategies for Cell Line Storage and Management

Mammalian Cell Culture Without Ascites

Mammalian Cell Culture Without Ascites Mammalian cell culture involves the growth of cells in a medium which is external to their tissue of origin. It is a useful tool for pharmaceutical, clinical, and research applications. When cells are isolated from their original animal tissues, they can be expanded and studied in culture in relation to … Continue reading Mammalian Cell Culture Without Ascites

Cell Culture Clarified Supernatant vs. Purified Antibodies

Cell Culture Clarified Supernatant vs. Purified Antibodies The purification of antibodies involves the specific isolation or selective enrichments of antibodies derived from polyclonal antibodies (serum), cell culture supernatant of monoclonal antibodies (hybridoma cell line), or ascites fluid. The method of purification ranges from highly specific to very crude. Below we cover some of the features … Continue reading Cell Culture Clarified Supernatant vs. Purified Antibodies