Monoclonal Antibody Production

At Cell Culture Company, we are fully equipped to provide custom monoclonal antibody production services. We have produced thousands of custom monoclonal antibodies with high specificity and high affinity. Our highly experienced team has the capability and expertise to perform large-scale antibody production.

Cell Culture Company offers a wide range of services, including purification and downstream processing for monoclonal antibodies.

Producing Monoclonal Antibodies

Monoclonal antibody (mAb) production is critical to the research and treatment of many infectious and non-infectious diseases. Designing and generating custom monoclonal antibodies has proven particularly helpful in treating certain types of cancer. The monoclonal antibodies produced at Cell Culture Company have been used as reagents for research, diagnostics, and product development.

Producing custom monoclonal antibodies is demanding, technical, and time-consuming. Clients may provide our team with their antibody-producing hybridoma or other cell line. The scientists at Cell Culture Company can provide monoclonal antibodies tailored to customer specification.

Standard Monoclonal Antibody Production Process

A traditional monoclonal antibody manufacturing process involves immunizing mice, producing hybridomas, screening the clones, and scaling up the clone production. At Cell Culture Company we offer an alternative, easy-to-scale, perfusion-based bioreactor approach to monoclonal antibody production.

Cells are cultured to inoculate a single-use hollow fiber cartridge, in which a consistent flow of media delivers nutrients across the semi-permeable fibers. This bioreactor environment is monitored and maintained at ideal conditions for antibody production. A continuous, concentrated stream of product is harvested from the bioreactor over several weeks to months.

Cell Culture Company can effectively scale up the clone producing antibodies and expand the production of the hybridoma cell line for clients.

Contact us today for inquiries regarding our unique process for monoclonal antibody production.