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Why Mycoplasma Testing Is Critical for Mammalian Cell Cultures

Why Mycoplasma Testing Is Critical for Mammalian Cell Cultures Introduction Mycoplasma contamination is one of the most persistent and problematic threats in mammalian cell culture. These tiny, bacteria can silently infiltrate cultures, distorting experimental results and compromising the integrity of cell culture production. Despite their size, their impact is enormous ranging from altered cell growth … Continue reading Why Mycoplasma Testing Is Critical for Mammalian Cell Cultures

What the FDA’s CAR-T REMS Removal Means for the Future of Cell Therapy Manufacturing

What the FDA’s CAR-T REMS Removal Means for the Future of Cell Therapy Manufacturing A New Era for Autologous CAR-T Therapies In a pivotal move for the field of cell and gene therapy, the FDA recently eliminated the Risk Evaluation and Mitigation Strategies (REMS) requirements for autologous CAR-T therapies. This recent FDA CAR-T REMS removal … Continue reading What the FDA’s CAR-T REMS Removal Means for the Future of Cell Therapy Manufacturing

Understanding Cryopreservation: A Vital Tool for Cell Culture and Biotechnology

Understanding Cryopreservation: A Vital Tool for Cell Culture and Biotechnology Cryopreservation is a key technique in modern biotechnology. It allows researchers to store living cells and biological samples at ultra-low temperatures—typically in liquid nitrogen—without losing viability. This method is essential for long-term storage and repeatable results. Why Cryopreservation Matters Consistency is critical in both research … Continue reading Understanding Cryopreservation: A Vital Tool for Cell Culture and Biotechnology

Cell Counting and Viability Assessment in Mammalian Cell Culture

Cell Counting and Viability Assessment in Mammalian Cell Culture Accurate cell counting and viability assessment are fundamental steps in mammalian cell culture. These procedures guide decisions in downstream applications, such as seeding density, expansion timing, and treatment concentrations. By understanding these techniques, researchers can improve reproducibility and ensure the success of their experiments. Importance of … Continue reading Cell Counting and Viability Assessment in Mammalian Cell Culture

Best Practices for Media Preparation and Exchange in Mammalian Cell Culture

Best Practices for Media Preparation and Exchange in Mammalian Cell Culture Media preparation and exchange are foundational tasks in mammalian cell culture. These processes directly affect cell growth, health, and experimental reproducibility. Therefore, researchers must follow strict protocols to ensure optimal results. Why Media Quality Matters Cell culture media supplies nutrients, growth factors, and the … Continue reading Best Practices for Media Preparation and Exchange in Mammalian Cell Culture