Understand the Uses and Benefits of Recombinant Antibodies
Recombinant antibodies (rAbs), which are genetically engineered, are forms of monoclonal antibodies produced at the genomic level by the means of in-vitro manipulation. With these antibodies, there is appropriate use with a range of cell lines, including bacterial, mammalian, insect, and yeast origin. At Cell Culture Company, we are your source for monoclonal and recombinant antibody production to match the customized needs of our customers.
Benefits of Recombinant Antibodies
There are several characteristics to recombinant antibodies that have given them continuing favor and preference in the eyes of researchers. Some of these characteristics we describe below:
1. Unsurpassed Replicability and Consistency
In contrast to more traditional forms of antibody production, the generation of antibodies revolves around a group of unique genes which makes their production exceptionally reliable and controllable. With replicability and consistency, researchers can avoid issues such as gene mutation, gene loss, and the drift of cell lines that can sometimes occur with other antibody production, resulting in a resolving of differences between batches and dependable results.
2. Easy to Manipulate
The methods of recombinant antibody production enable extensive control and monitoring of the antigen during production. This is in contrast to what occurs with much of the trial and error during traditional antibody production.
3. Higher Specificity and Sensitivity
The production of recombinant antibodies allows for the generation of a very desirable quality of antibodies.
4. Easy Isotype Conversion
The production of antibodies enables modifications in sequence to accommodate specific needs after the establishment of the desired fragment.
5. Animal-Free Technology
Recombinant antibodies that stem from human or synthetic collections are not associated with animal immunity. As such, concerns over the welfare of animals in connection with techniques such as immunizations and euthanasia to produce antibodies is removed.
Recombinant Antibody Applications
Recombinant antibodies are just blossoming in their use and applications. They are new in toxicological research and biomedical science. Thus far, treatment breakthroughs connected with their use. Including, viral infections, auto-immune diseases, cerebrovascular disease, cardiovascular disease, tumors, and Alzheimer’s disease.
As additional research is performed, more understanding and treatment possibilities using recombinant antibodies is expected, including the prevention of more illnesses.
To learn about the recombinant antibody production services our team offers at Cell Culture Company, give us a call today at 763.786.0302 or leave us a message using our contact form.
