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Managing Ascites Troubles: A Mouse-Free Approach

Despite decades of advancements in in vitro antibody production methods, many of the world’s largest diagnostics and reagents companies are still manufacturing in mice. The ascites method of manufacturing is inherently problematic due to batch inconsistency, supply chain unreliability, quality issues, and the ethics of using animals when alternatives are available. In this post, we’ll … Continue reading Managing Ascites Troubles: A Mouse-Free Approach

The Perfusion Revolution

Article contributed by Brittni Peterson, PhD, and Emily Wozniak, PhD Adopting new technologies is a challenge in heavily regulated environments, as innovation is often stymied in favor of safer, established technologies. This is especially true of the biomanufacturing industry. Mainstream bioreactors have been improved only incrementally since the original fermenters that produced ingredients like citric … Continue reading The Perfusion Revolution

Finding your fit: Small-scale CDMOs

Article Contributed by Brittni Peterson, PhD and Emily Wozniak, PhD Large-scale therapeutic products (many kg’s per year) command respect from contract manufacturers. These products generally consume dedicated manufacturing suites for multiple years and guarantee premium budgets. Their owners are often large pharmaceutical companies with significant resources and a track record of paying for the best. … Continue reading Finding your fit: Small-scale CDMOs