Downstream Services

With a combined total of over 50+ years of experience, our staff understands the challenges associated with developing and running a robust downstream process. 

TECHNICAL SERVICES AND SUPPORT

Process development
Process evaluation, and validation
Clinical and Commercial Manufacturing
Technology Transfer
Comparability
Quality by design
Regulatory Support

CAPTURE CHROMATOGRAPHY

Protein A, G Affinity
Ceramic Hydroxyapatite (CHT)
Metal Affinity

FINISH PROCESSING

Formulation
Conjugation
Final Fill

ANTIBODY AND NON-ANTIBODY PROTEIN-BASED PURIFICATION

IgM
Fc-fusion proteins
His tagged proteins

POLISHING

Cation/Anion exchange chromatography
Size Exclusion Chromatography (SEC)
Viral inactivation, filtration, and clearance
TFF/Diafiltration