Cell Culture Company has produced two fully automated single-use hollow fiber bioreactors (the AutovaxID and the AcuSyst-Xcellerator) and one semi-automated bioreactor (the AcuSyst-Maximizer).
This automation provides numerous benefits:
- Ensure reproducibility: Automatically maintained process parameters allows for lot-to-lot consistency as you scale up your technology and process to meet manufacturing requirements.
- Reduce labor: Performing in-process monitoring and responding to changes in metabolic parameters can be a significant burden of labor. C3's automation reduces the amount of labor necessary during a production run.
- Decrease contamination risk: the combination of reduced hands-on manual labor and the closed-loop system reduces the risk of introduced contamination throughout the run.
- C3's bioreactors monitor and control:
- Incubator temperature
- Refrigerator temperature
- Media perfusion rate
- Lactate levels
- EC (cell-side) cycling